CBR1, carbonyl reductase 1, 873

N. diseases: 100; N. variants: 2
Disease: Kidney Failure, Chronic ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic 		0.500 Biomarker disease RGD Effect of experimental kidney disease on the functional expression of hepatic reductases. 25332430 2015
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic 		0.500 Biomarker disease CTD_human These results demonstrate a trend toward decreased functional expression of selective hepatic reductases in ESRD livers, which may partially explain altered pharmacokinetics of CBR1 drug substrates in ESRD. 26282591 2015