TNFSF10, TNF superfamily member 10, 8743

N. diseases: 445; N. variants: 10
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.320 Therapeutic group CTD_human Fenretinide up-regulates DR5/TRAIL-R2 expression via the induction of the transcription factor CHOP and combined treatment with fenretinide and TRAIL induces synergistic apoptosis in colon cancer cell lines. 17273769 2007
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.320 Biomarker group LHGDN Photochemically mediated delivery of AdhCMV-TRAIL augments the TRAIL-induced apoptosis in colorectal cancer cell lines. 17012835 2006
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.320 Biomarker group BEFREE The outgrowth of human colorectal tumors grown in mice was completely blocked by transduction with AAV.TRAIL in vitro, while in vivo transduction significantly inhibited the growth of established tumors. 14999225 2004