TNFSF10, TNF superfamily member 10, 8743

N. diseases: 445; N. variants: 10
Disease: Immune-mediated hepatitis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4324396
Disease: Immune-mediated hepatitis
Immune-mediated hepatitis 		0.010 Biomarker disease BEFREE These data provide new insights into TRAIL-induced necroptosis with PARP-1 being active effector downstream of RIPK1/RIPK3 initiators and suggest that pharmacological inhibitors of RIPKs and PARP-1 could be new treatment options for immune-mediated hepatitis. 22814620 2012