ADAM9, ADAM metallopeptidase domain 9, 8754

N. diseases: 109; N. variants: 6
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0017638
Disease: Glioma
Glioma
0.040 AlteredExpression disease BEFREE ADAM9 has been found over-expressed in several solid tumors entities such as glioma, melanoma, prostate cancer, pancreatic ductal adenocarcinoma, gastric, breast, lung, and liver cancers. 29550974 2018
CUI: C0017638
Disease: Glioma
Glioma
0.040 Biomarker disease BEFREE Collective results suggested that galangin may act as an effective chemotherapeutic agent for glioma cancer depending on its ability to bring about ADAM9 and Erk1/2 activation. 29115634 2018
CUI: C0017638
Disease: Glioma
Glioma
0.040 Biomarker disease BEFREE In addition, a disintegrin and metalloproteinase 9 (ADAM9) was identified as a novel direct target gene of miR-140 in glioma. 27498787 2016
CUI: C0017638
Disease: Glioma
Glioma
0.040 AlteredExpression disease BEFREE These results suggest that ADAM9 mRNA expression is associated with tumor grade and histological type in gliomas and can serve as an independent prognostic factor, specifically in LGG patients. 27571068 2016