CD164, CD164 molecule, 8763

N. diseases: 44; N. variants: 1
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4283893
Disease: DEAFNESS, AUTOSOMAL DOMINANT 66
DEAFNESS, AUTOSOMAL DOMINANT 66
0.600 Biomarker disease GENOMICS_ENGLAND A Novel Locus Harbouring a Functional CD164 Nonsense Mutation Identified in a Large Danish Family with Nonsyndromic Hearing Impairment. 26197441 2015
CUI: C4283893
Disease: DEAFNESS, AUTOSOMAL DOMINANT 66
DEAFNESS, AUTOSOMAL DOMINANT 66
0.600 Biomarker disease CLINGEN A Novel Locus Harbouring a Functional CD164 Nonsense Mutation Identified in a Large Danish Family with Nonsyndromic Hearing Impairment. 26197441 2015
CUI: C4283893
Disease: DEAFNESS, AUTOSOMAL DOMINANT 66
DEAFNESS, AUTOSOMAL DOMINANT 66
0.600 Biomarker disease CTD_human
CUI: C3711374
Disease: Nonsyndromic Deafness
Nonsyndromic Deafness
0.310 GeneticVariation disease BEFREE In this study we used SNP-based linkage analysis and follow up microsatellite markers to identify a novel locus (DFNA66) on chromosome 6q15-21 (LOD 5.1) in a large Danish family with dominantly inherited NSHI. 26197441 2015
CUI: C3711374
Disease: Nonsyndromic Deafness
Nonsyndromic Deafness
0.310 Biomarker disease CLINGEN In this study we used SNP-based linkage analysis and follow up microsatellite markers to identify a novel locus (DFNA66) on chromosome 6q15-21 (LOD 5.1) in a large Danish family with dominantly inherited NSHI. 26197441 2015
CUI: C0000786
Disease: Spontaneous abortion
Spontaneous abortion
0.300 Biomarker phenotype CTD_human Gene expression in cultured endometrium from women with different outcomes following IVF. 18539642 2008
CUI: C0000822
Disease: Abortion, Tubal
Abortion, Tubal
0.300 Biomarker phenotype CTD_human Gene expression in cultured endometrium from women with different outcomes following IVF. 18539642 2008
CUI: C3830362
Disease: Early Pregnancy Loss
Early Pregnancy Loss
0.300 Biomarker phenotype CTD_human Gene expression in cultured endometrium from women with different outcomes following IVF. 18539642 2008
CUI: C4552766
Disease: Miscarriage
Miscarriage
0.300 Biomarker disease CTD_human Gene expression in cultured endometrium from women with different outcomes following IVF. 18539642 2008
CUI: C0200641
Disease: Blood basophil count (lab test)
Blood basophil count (lab test)
0.100 GeneticVariation phenotype GWASCAT Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. 29403010 2018
Sensorineural Hearing Loss (disorder)
0.100 Biomarker disease HPO
CUI: C1861403
Disease: Variable expressivity
Variable expressivity
0.100 Biomarker phenotype HPO
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.060 Biomarker group BEFREE The immunohistochemistry (IHC) was performed to evaluate the associations between the expression level of CD164 and clinical-pathological features of patients, and IHC was used to analyze the relationship between CD164 and CXCR4 in tumor tissues. 30022623 2018
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.060 Biomarker group BEFREE To further characterize CD164 as a potential biomarker for malignant CD4<sup>+</sup> T cells, CD164<sup>+</sup> and CD164<sup>-</sup>CD4<sup>+</sup> T cells isolated from patients with high-circulating tumor burden, B2 stage, and medium/low tumor burden, B1-B0 stage, were assessed for the expression of genes reported to differentiate SS from normal controls, and associated with malignancy and poor prognosis. 27766406 2017
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.060 Biomarker group BEFREE CD164 is regarded to be a potential promotor of tumor growth. 28259931 2017
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.060 Biomarker group BEFREE In conclusion, we have provided evidence that CD164 promotes the growth of lung tumor-initiating cells with stem cell properties and induces tumor growth and drug resistance through Akt/mTOR signaling. 28903328 2017
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.060 Biomarker group BEFREE Our results suggest that CD164 can serve as a marker for diagnosis and for monitoring progression of cutaneous T-cell lymphoma (CTCL)/SS and that FCRL3 expression correlates with a high circulating tumor burden. 23792457 2014
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.060 AlteredExpression group BEFREE The clinicopathological correlation analysis showed that the upregulation of CD164 protein was significantly associated with tumor grade and metastasis. 24094005 2013
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.040 Biomarker phenotype BEFREE CD164 regulates proliferation, progression, and invasion of human glioblastoma cells. 31007847 2019
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.040 AlteredExpression phenotype BEFREE High level of CD164 was related to the distant metastasis and vascular invasion of bladder cancer patients. 30022623 2018
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.040 AlteredExpression phenotype BEFREE High level of CD164 was related to the distant metastasis and vascular invasion of bladder cancer patients. 30022623 2018
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.040 AlteredExpression phenotype BEFREE Emerging evidence indicates that elevated CD164 expression is associated with aggressive metastasis, advanced stages, and shorter overall survival in lung cancer. 28903328 2017
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.040 AlteredExpression phenotype BEFREE The clinicopathological correlation analysis showed that the upregulation of CD164 protein was significantly associated with tumor grade and metastasis. 24094005 2013
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.040 Biomarker phenotype BEFREE Given that IMP3 is an mRNA-binding protein, we determined that it binds several key mRNAs that could contribute to migration and invasion, including CD164 (endolyn) and MMP9. 22266872 2012
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.040 Biomarker phenotype LHGDN Our findings suggest that CD164 may participate in the localization of prostate cancer cells to the marrow and is further evidence that tumor metastasis and hematopoietic stem cell trafficking may involve similar processes. 16859559 2006