TNFRSF14, TNF receptor superfamily member 14, 8764

N. diseases: 100; N. variants: 3
Disease: Primary Cutaneous Follicle Center Lymphoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1333171
Disease: Primary Cutaneous Follicle Center Lymphoma
Primary Cutaneous Follicle Center Lymphoma 		0.010 GeneticVariation disease BEFREE BCL2 gene break or 1p36 deletion did not impact the prognosis; however, they showed association with advanced stages at diagnosis (p = 0.016) and a tendency with shorter event free survival (p = 0.052).In conclusion, 1p36 deletion co-occurs with acquired TNFRSF14 mutations, suggesting a role of this tumor suppressor gene in the development of a subgroup of PCFCL. 29858685 2018