GALR2, galanin receptor 2, 8811

N. diseases: 41; N. variants: 2
Disease: Depressed mood ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0344315
Disease: Depressed mood
Depressed mood 		0.020 GeneticVariation phenotype BEFREE Here we report that variants in genes for galanin (GAL) and its receptors (GALR1, GALR2, GALR3), despite their disparate genomic loci, conferred increased risk of depression and anxiety in people who experienced childhood adversity or recent negative life events in a European white population cohort totaling 2,361 from Manchester, United Kingdom and Budapest, Hungary. 24706871 2014
CUI: C0344315
Disease: Depressed mood
Depressed mood 		0.020 Biomarker phenotype BEFREE Phenotypic analysis of GalR2 knockout mice in anxiety- and depression-related behavioral tests. 18554714 2008