CES2, carboxylesterase 2, 8824

N. diseases: 87; N. variants: 1
Disease: Steatohepatitis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2711227
Disease: Steatohepatitis
Steatohepatitis 		0.020 Biomarker disease BEFREE In mice, obesity reduced CES2, whereas adenoviral delivery of human CES2 reversed hepatic steatosis, improved glucose tolerance, and decreased inflammation. 28099843 2017
CUI: C2711227
Disease: Steatohepatitis
Steatohepatitis 		0.020 AlteredExpression disease BEFREE Restoration of hepatic CES2 expression in db/db or HFD-fed mice markedly ameliorates liver steatosis and insulin resistance. 26806650 2016