CES2, carboxylesterase 2, 8824

N. diseases: 87; N. variants: 1
Disease: Hyalinosis, Systemic ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2745948
Disease: Hyalinosis, Systemic
Hyalinosis, Systemic 		0.020 GeneticVariation disease BEFREE A 5' untranslated region polymorphism in the carboxylesterase 2 gene was associated with HFS. 25601966 2015
CUI: C2745948
Disease: Hyalinosis, Systemic
Hyalinosis, Systemic 		0.020 GeneticVariation disease BEFREE The presence of two polymorphisms (CDD 943insC and CES 2 Exon3 6046 G/A) were associated with a non-statistically significant higher incidence of grade 3 hand-foot syndrome (HFS) (p=0.07) and grade 3-4 diarrhoea (p=0.09), respectively. 18473752 2008