NRP1, neuropilin 1, 8829

N. diseases: 246; N. variants: 13
Disease: ANOPHTHALMIA AND PULMONARY HYPOPLASIA ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1832661
Disease: ANOPHTHALMIA AND PULMONARY HYPOPLASIA
ANOPHTHALMIA AND PULMONARY HYPOPLASIA 		0.030 Biomarker disease BEFREE Noting that the cyclic peptide iRGD mediates tumor targeting and penetration through interactions with α<sub>v</sub>β<sub>3/5</sub> integrins and neuropilin-1, we hypothesized that "tandem" peptides combining a cell-penetrating peptide and iRGD can encapsulate siRNA to form tumor-penetrating nanocomplexes (TPN) capable of delivering siRNA to PDAC. 30097486 2018
CUI: C1832661
Disease: ANOPHTHALMIA AND PULMONARY HYPOPLASIA
ANOPHTHALMIA AND PULMONARY HYPOPLASIA 		0.030 Biomarker disease BEFREE We conclude that VEGFR2/NRP1 trans-complex formation is an independent predictor of PDAC patient survival.© 2018 The Authors. 30027561 2018
CUI: C1832661
Disease: ANOPHTHALMIA AND PULMONARY HYPOPLASIA
ANOPHTHALMIA AND PULMONARY HYPOPLASIA 		0.030 AlteredExpression disease BEFREE We report herein a positive correlation between NRP-1 levels, EndMT and fibrosis in human PDAC xenografts. 27542226 2016