HDAC3, histone deacetylase 3, 8841

N. diseases: 179; N. variants: 5
Disease: Colon Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0699790
Disease: Colon Carcinoma
Colon Carcinoma 		0.020 Biomarker disease BEFREE HDAC1 and HDAC3 are up-regulated in colon cancer cells and in primary colon cancer, and siRNA (small interfering RNA)-mediated silencing of HDAC1 and HDAC3 in colon cancer cells induces apoptosis. 18789002 2009
CUI: C0699790
Disease: Colon Carcinoma
Colon Carcinoma 		0.020 AlteredExpression disease BEFREE Silencing of HDAC3 expression in colon cancer cell lines resulted in growth inhibition, a decrease in cell survival, and increased apoptosis. 16533812 2006