KAT2B, lysine acetyltransferase 2B, 8850

N. diseases: 116; N. variants: 9
Disease: Diabetes Mellitus ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.030 Biomarker group BEFREE p300/CBP Associated Factor (PCAF) bromodomain (BRD), a lysine acetyltransferases, has emerged as a promising drug target as its dysfunction is linked to onset and progression of several diseases like cancer, diabetes, AIDS, etc. 29228881 2018
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.030 Biomarker group BEFREE On multivariable analyses, CAF was independent from established risk factors (GRACE-score, diabetes mellitus, mean heart rate, heart rate variability). 29121716 2017
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.030 Biomarker group BEFREE Our results suggest that PCAF might be a potential pharmacological target for developing agents against metabolic disorders associated with hyperglycemia, such as obesity and diabetes. 25497092 2014