APLN, apelin, 8862

N. diseases: 226; N. variants: 11
Disease: Primary malignant neoplasm ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		0.090 Biomarker group BEFREE Apelin plays an important part in regulating blood pressure, metabolism, and the development of cancer. 30755060 2019
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		0.090 Biomarker group BEFREE Moreover, better understanding the process through which apelin regulates cancer development is still necessary to the creation of novel anti-cancer therapy. 30127323 2018
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		0.090 Biomarker group BEFREE Moreover, we put forward an indication of apelin as a biomarker predicting cardiac diseases and various types of cancer. 29875677 2018
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		0.090 AlteredExpression group BEFREE In this study, we examined the expression of apelin and its receptor in non-cancer and cancer cell lines derived from the human ovary, and further explored whether the expression of apelin and its receptor is modulated by BPA and its derivatives. 28111160 2017
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		0.090 AlteredExpression group BEFREE To study the association between Apelin expression and the clinical features and postoperative prognosis in patients with gastric cancer (Int J Cancer 136:2388-2401, 2015). 27733135 2016
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		0.090 AlteredExpression group BEFREE Apelin levels were evaluated in a cohort of 95 patients affected by different varieties of cancer. 24469934 2015
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		0.090 Biomarker group BEFREE Apelin‑13 has been shown to promote tumor proliferation in various types of cancer, including hepatocellular, lung and ovarian cancer. 26135903 2015
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		0.090 Biomarker group BEFREE Using a cancer profiling array, our laboratory has shown that apelin gene is up-regulated in half of colon adenocarcinomas. 24316062 2014
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		0.090 AlteredExpression group BEFREE Moreover, it also provides the first evidence for a direct association of apelin expression with clinical outcome in a human cancer. 20581707 2010