PER3, period circadian regulator 3, 8863

N. diseases: 122; N. variants: 19
Disease: Diabetes ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011847
Disease: Diabetes
Diabetes 		0.030 GeneticVariation disease BEFREE PER3(5) carriers are inclined to have a morning preference and associated with higher risk of bipolar disorder and diabetes. 26440425 2015
CUI: C0011847
Disease: Diabetes
Diabetes 		0.030 GeneticVariation disease BEFREE Our results are compatible with a role for UII in glucose homeostasis and diabetes although we cannot rule out the possibility that PER3 gene may underlie the reported associations. 21559414 2011
CUI: C0011847
Disease: Diabetes
Diabetes 		0.030 AlteredExpression disease BEFREE In study 2, leucocytes obtained from patients with diabetes expressed significantly (p < 0.05) lower transcript levels of BMAL1, PER1 and PER3 compared with leucocytes from control individuals, and transcript expression was inversely correlated with HbA(1c) levels (rho = -0.47 to -0.55, p < 0.05). 18974966 2009