SQSTM1, sequestosome 1, 8878

N. diseases: 470; N. variants: 43
Disease: Adult Glioblastoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0278878
Disease: Adult Glioblastoma
Adult Glioblastoma 		0.040 Biomarker disease BEFREE Inhibition of WNT-CTNNB1 signaling upregulates SQSTM1 and sensitizes glioblastoma cells to autophagy blockers. 29313411 2018
CUI: C0278878
Disease: Adult Glioblastoma
Adult Glioblastoma 		0.040 Biomarker disease BEFREE Nrf2 and SQSTM1/p62 jointly contribute to mesenchymal transition and invasion in glioblastoma. 31444413 2019
CUI: C0278878
Disease: Adult Glioblastoma
Adult Glioblastoma 		0.040 Biomarker disease BEFREE The autophagy-associated factors DRAM1 and p62 regulate cell migration and invasion in glioblastoma stem cells. 22525272 2013
CUI: C0278878
Disease: Adult Glioblastoma
Adult Glioblastoma 		0.040 AlteredExpression disease BEFREE The effect of extracellular high-mobility group box 1 (HMGB1) protein on glioblastoma (GBM) progression is still controversial. p62 is overexpressed in glioma cells, and has been associated with the malignant features and poor prognosis of GBM patients. 31037147 2019