SQSTM1, sequestosome 1, 8878

N. diseases: 470; N. variants: 43
Disease: Adult Glioblastoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0278878
Disease: Adult Glioblastoma
Adult Glioblastoma 		0.040 AlteredExpression disease BEFREE The effect of extracellular high-mobility group box 1 (HMGB1) protein on glioblastoma (GBM) progression is still controversial. p62 is overexpressed in glioma cells, and has been associated with the malignant features and poor prognosis of GBM patients. 31037147 2019
CUI: C0278878
Disease: Adult Glioblastoma
Adult Glioblastoma 		0.040 Biomarker disease BEFREE Nrf2 and SQSTM1/p62 jointly contribute to mesenchymal transition and invasion in glioblastoma. 31444413 2019
CUI: C0278878
Disease: Adult Glioblastoma
Adult Glioblastoma 		0.040 Biomarker disease BEFREE Inhibition of WNT-CTNNB1 signaling upregulates SQSTM1 and sensitizes glioblastoma cells to autophagy blockers. 29313411 2018
CUI: C0278878
Disease: Adult Glioblastoma
Adult Glioblastoma 		0.040 Biomarker disease BEFREE The autophagy-associated factors DRAM1 and p62 regulate cell migration and invasion in glioblastoma stem cells. 22525272 2013