SQSTM1, sequestosome 1, 8878

N. diseases: 470; N. variants: 43
Disease: Adult Liver Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0220630
Disease: Adult Liver Carcinoma
Adult Liver Carcinoma 		0.040 AlteredExpression disease BEFREE Evidence has shown that p62 is upregulated in different cancers and promotes tumour growth, such as in liver cancer and lung cancer. 30793399 2019
CUI: C0220630
Disease: Adult Liver Carcinoma
Adult Liver Carcinoma 		0.040 Biomarker disease BEFREE By demonstrating the regulation of glycolysis by autophagy through the TRAF6- and SQSTM1-mediated ubiquitination system, our study may open an avenue for developing a glycolysis-targeting therapeutic intervention for treatment of autophagy-impaired liver cancer. 28980855 2018
CUI: C0220630
Disease: Adult Liver Carcinoma
Adult Liver Carcinoma 		0.040 Biomarker disease BEFREE p62/SQSTM1-Dr. Jekyll and Mr. Hyde that prevents oxidative stress but promotes liver cancer. 27404485 2016
CUI: C0220630
Disease: Adult Liver Carcinoma
Adult Liver Carcinoma 		0.040 AlteredExpression disease BEFREE Aberrant expression of fetal RNA-binding protein p62 in liver cancer and liver cirrhosis. 11549587 2001