ZPR1, ZPR1 zinc finger, 8882

N. diseases: 64; N. variants: 35
Disease: Respiratory distress ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0476273
Disease: Respiratory distress
Respiratory distress 		0.020 Biomarker phenotype BEFREE Identification of ZPR1 and HoxA5 as potential targets provides a paradigm for developing strategies to treat respiratory distress in SMA. 28811488 2017
CUI: C0476273
Disease: Respiratory distress
Respiratory distress 		0.020 AlteredExpression phenotype BEFREE We report that the reduced ZPR1 expression causes increase in the loss of motor neurons, hypermyelination in phrenic nerves, increase in respiratory distress and disease severity and reduces the lifespan of SMA mice. 22422766 2012