CCNA2, cyclin A2, 890

N. diseases: 90; N. variants: 5
Disease: Liver carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.050 Biomarker disease BEFREE Among them, PLK1 and CCNA2 were suggested to be prognostic factors for liver carcinoma. 29843214 2018
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.050 GeneticVariation disease BEFREE Cyclin A2 or E1 alterations define a homogenous entity of aggressive HCC, mostly developed in non-cirrhotic patients, characterized by a transcriptional activation of E2F and ATR pathways and a high frequency of RB1 and PTEN inactivation. 30531861 2018
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.050 AlteredExpression disease BEFREE In addition, evidence suggested that either miR-22 silencing or FXR knockdown reversed the diminished CCNA2 expression as well as cell proliferation inhibition caused by WA treatment and WA inhibited tumor masses in vivo in a subcutaneous xenograft mouse model of HCC. 27738335 2016
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.050 Biomarker disease LHGDN Cyclins and cyclin-dependent kinases: comparative study of hepatocellular carcinoma versus cirrhosis. 12601350 2003
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.050 GeneticVariation disease BEFREE Hepatitis B virus integration in a cyclin A gene in a hepatocellular carcinoma. 1967822 1990