BCL10, BCL10 immune signaling adaptor, 8915

N. diseases: 205; N. variants: 14
Disease: Mesothelioma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0025500
Disease: Mesothelioma
Mesothelioma 		0.120 GeneticVariation disease BEFREE Since BCL10 also does not possess mutations at the genomic DNA level, it can be ruled out as a gene involved in the pathogenesis of MM and colorectal cancer. 11107182 2001
CUI: C0025500
Disease: Mesothelioma
Mesothelioma 		0.120 GeneticVariation disease BEFREE According to the LOH study at intragenic polymorphic sites, deletion of Bcl10 in informative cases was detected in 50% of malignant mesotheliomas, 33% of gastric carcinomas, 23% of breast carcinomas, 20% of hepatocellular carcinomas, 17% of lymphomas, 15% of colorectal carcinomas, 13% of laryngeal carcinomas, and 10% of male germ cell tumors (GCTs). 10582682 1999
CUI: C0025500
Disease: Mesothelioma
Mesothelioma 		0.120 CausalMutation disease CLINVAR