MGAM, maltase-glucoamylase, 8972

N. diseases: 95; N. variants: 18
Disease: Adenocarcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma 		0.010 AlteredExpression group BEFREE This phenolic-rich extract inhibited the lipid oxidation of Wistar rat brain (IC<sub>50</sub> = 863.0 mg GAE/L), inhibited α-glucosidase activity (IC<sub>50</sub> = 435.4 µg/mL), protected human erythrocytes against mechanical hemolysis at different osmolarity conditions, and showed cytotoxic/antiproliferative effects against human ileocecal adenocarcinoma cells (HCT8; IC<sub>50</sub> = 552.6 µg/mL) but no cytotoxicity toward noncancerous human lung fibroblast (IMR90). 31721214 2019