MGAM, maltase-glucoamylase, 8972

N. diseases: 95; N. variants: 18
Disease: Caffeine related disorders ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0236734
Disease: Caffeine related disorders
Caffeine related disorders 		0.010 AlteredExpression group BEFREE Among them, Compound (5) was identified as the most potent inhibitor of GP-α and α-glucosidase and its GP-α inhibitory activity (IC<sub>50</sub> = 45.08 μM) was 10-fold higher than that of caffeine (IC<sub>50</sub> = 457.34 μM), and α-glucosidase inhibitory activity (IC<sub>50</sub> = 26.41 μM) was 5.5-fold higher than that of acarbose (IC<sub>50</sub> = 145.83 μM), respectively. 28166749 2017