WNT3A, Wnt family member 3A, 89780

N. diseases: 141; N. variants: 5
Disease: Barrett Esophagus ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004763
Disease: Barrett Esophagus
Barrett Esophagus 		0.020 Biomarker disease BEFREE A loss of Wnt3a expression was observed beginning from the metaplastic cell line CP-A towards dysplasia (CP-B) and EAC (OE33 and OE19), confirmed by a lower staining index of WNT3A in Barrett's metaplasia and EAC, than in squamous epithelium specimens. 30841855 2019
CUI: C0004763
Disease: Barrett Esophagus
Barrett Esophagus 		0.020 AlteredExpression disease BEFREE Wnt target genes (AXIN2, c-MYC, Cyclin D1, Dkk1) and Wnt3a were significantly upregulated in nondysplastic BE compared with squamous mucosa. 26297437 2015