Disease: Inflammatory pain ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0234251
Disease: Inflammatory pain
Inflammatory pain 		0.070 Biomarker phenotype BEFREE TRPA1 is an excitatory ion channel and is involved in sensory processes including thermal nociception and inflammatory pain. 30238636 2019
CUI: C0234251
Disease: Inflammatory pain
Inflammatory pain 		0.070 AlteredExpression phenotype BEFREE The isolated polyacteylenes were evaluated for their modulation of six thermo-TRP channels and they revealed a selective activity on TRPA1, an ion channel involved in the mediation of neuropathic and inflammatory pain. 30018233 2018
CUI: C0234251
Disease: Inflammatory pain
Inflammatory pain 		0.070 Biomarker phenotype BEFREE Although TRPA1, SP, histamine and 5-hydroxytryptamine (5-HT) have recognized contribution to nociceptive mechanisms, little is known about how they interact with each other to mediate inflammatory pain in vivo. 27904941 2017
CUI: C0234251
Disease: Inflammatory pain
Inflammatory pain 		0.070 Biomarker phenotype BEFREE These findings suggest that TRPA1 is a molecular target for OxPAPC and OxPAPC may contribute to chronic inflammatory pain through TRPA1 activation. 27812120 2016
CUI: C0234251
Disease: Inflammatory pain
Inflammatory pain 		0.070 Biomarker phenotype BEFREE TRPV1 and TRPA1 channels in inflammatory pain: elucidating mechanisms. 22211974 2011
CUI: C0234251
Disease: Inflammatory pain
Inflammatory pain 		0.070 Biomarker phenotype BEFREE However, it is not known whether tissue injury also produces endogenous proalgesic factors that activate TRPA1 directly to augment inflammatory pain. 17684094 2007
CUI: C0234251
Disease: Inflammatory pain
Inflammatory pain 		0.070 Biomarker phenotype BEFREE Here, we show that a functional interaction of PAR2 and TRPA1 in dorsal root ganglion (DRG) neurons could contribute to the sensation of inflammatory pain. 17571167 2007