Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007222
Disease: Cardiovascular Diseases
Cardiovascular Diseases
0.040 Biomarker group BEFREE Hypomethylation of AHRR or F2RL3 is a risk factor for lung cancer and shorter telomere length a risk factor for cardiovascular disease. 31369996 2019
CUI: C0007222
Disease: Cardiovascular Diseases
Cardiovascular Diseases
0.040 Biomarker group BEFREE Conclusively, this review highlights the importance of PAR4 antagonists and its potential utility in different CVDs. 29443899 2018
CUI: C0007222
Disease: Cardiovascular Diseases
Cardiovascular Diseases
0.040 Biomarker group BEFREE Among them, 5 loci were validated and methylation at F2RL3 was reported in two large prospective studies to predict cardiovascular disease beyond the traditional risk factors. 27038728 2016
CUI: C0007222
Disease: Cardiovascular Diseases
Cardiovascular Diseases
0.040 GeneticVariation group BEFREE Recent studies linked tobacco smoke exposure to hypomethylation of the F2RL3 (coagulation factor II (thrombin) receptor-like 3) gene, a marker for cardiovascular disease prognosis and mortality. 26395445 2015