Disease: Tumor Progression ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0178874
Disease: Tumor Progression
Tumor Progression 		0.040 AlteredExpression phenotype BEFREE That PAR4 expression difference in tumor progression possibly makes PAR4 become a molecular mark of tumor diagnosis. 25030438 2014
CUI: C0178874
Disease: Tumor Progression
Tumor Progression 		0.040 Biomarker phenotype BEFREE Proteinase-activated receptors (PARs) are a subfamily of G protein-coupled receptors (GPCRs) with four members, PAR1, PAR2, PAR3 and PAR4, playing critical functions in hemostasis, thrombosis, embryonic development, wound healing, inflammation and cancer progression. 24215724 2013
CUI: C0178874
Disease: Tumor Progression
Tumor Progression 		0.040 Biomarker phenotype BEFREE At this PIN transition, the mutual induction of Par-4 and PTEN is an additional regulatory step in preventing cancer progression. 19625770 2009
CUI: C0178874
Disease: Tumor Progression
Tumor Progression 		0.040 AlteredExpression phenotype BEFREE This indicates that the downregulation of Par-4 by oncogenic Ras is a critical event in tumor progression. 10562548 1999