SLC13A2, solute carrier family 13 member 2, 9058

N. diseases: 19; N. variants: 0
Disease: Epithelial ovarian cancer ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0677886
Disease: Epithelial ovarian cancer
Epithelial ovarian cancer 		0.040 Biomarker disease BEFREE To evaluate the impact of an evidence-based triage algorithm to decide between primary debulking surgery (PDS) and neoadjuvant chemotherapy followed by interval debulking surgery (NACT/IDS) for advanced epithelial ovarian cancer (EOC). 31402165 2019
CUI: C0677886
Disease: Epithelial ovarian cancer
Epithelial ovarian cancer 		0.040 Biomarker disease BEFREE Key inclusion criteria were prospective clinical trials examining platinum-based NACT for stage II-IV epithelial ovarian cancer. 31818526 2019
CUI: C0677886
Disease: Epithelial ovarian cancer
Epithelial ovarian cancer 		0.040 GeneticVariation disease BEFREE For patients with advanced stage epithelial ovarian cancer (EOC), substantial emphasis has been placed on diagnostic tests that can discern which of two treatment options - primary cytoreductive surgery (PCS) or neoadjuvant chemotherapy followed by interval cytoreductive surgery (NACT+ICS) - optimizes patient-level outcomes. 29486993 2018
CUI: C0677886
Disease: Epithelial ovarian cancer
Epithelial ovarian cancer 		0.040 GeneticVariation disease BEFREE TP53 K351N mutation may be associated with induction of platinum resistance after NACT in advanced EOC. 24463159 2014