DIRAS3, DIRAS family GTPase 3, 9077

N. diseases: 50; N. variants: 0
Disease: Glioma ×
Source: BEFREE ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0017638
Disease: Glioma
Glioma 		0.020 Biomarker disease BEFREE We found over-expression of ARHI can also inhibit cancer cell proliferation, decrease tumorigenicity, and induce autophagic cell death in human glioma and inhibition of the late stage of autophagy can further enhance the antitumor effect of ARHI through inducing apoptosis in vitro or vivo. 31088402 2019
CUI: C0017638
Disease: Glioma
Glioma 		0.020 Biomarker disease BEFREE Taken together, these findings reveal a novel oncogenic role of DIRAS3 in the development and progression of glioma, which suggest that DIRAS3 could serve as a potential diagnostic marker and a promising therapeutic target of gliomas. 30266404 2018