PYGO2, pygopus family PHD finger 2, 90780

N. diseases: 37; N. variants: 1
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0017638
Disease: Glioma
Glioma
0.030 AlteredExpression disease BEFREE Further, we demonstrated that the involvement of Pygo2 in the activation of the Wnt pathway in human glioma progression is through up-regulation of the H3K4me3 (but not H3K4me2) by promoting the recruitment of the histone methyltransferase MLL1/MLL2 complex to Wnt target gene promoters. 26902498 2016
CUI: C0017638
Disease: Glioma
Glioma
0.030 Biomarker disease BEFREE In the current study, we investigated the role of Pygo2 in rat glioma C6 cells for the first time. 20361361 2011
CUI: C0017638
Disease: Glioma
Glioma
0.030 AlteredExpression disease BEFREE In the present study, Pygo2 expression was evaluated in 80 glioma tissue samples. 20204459 2010