MTA1, metastasis associated 1, 9112

N. diseases: 118; N. variants: 0
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2939419
Disease: Secondary Neoplasm
Secondary Neoplasm
0.100 Biomarker group BEFREE Metastasis-associated protein 1 (MTA1) is involved in development of tumors and metastases. 28589145 2017
CUI: C2939419
Disease: Secondary Neoplasm
Secondary Neoplasm
0.100 AlteredExpression group BEFREE Furthermore, detection of the changes in expression levels of metastasis‑associated gene 1 (MTA‑1) and tumor metastasis suppressor gene, non‑metastasis protein 23‑H1 (nm23‑H1), and the expression change of autophagy‑associated signal transduction pathway, phosphatidylinositol 3‑kinase (PI3K)/protein kinase B (PKB) kinase were analyzed. 27082164 2016
CUI: C2939419
Disease: Secondary Neoplasm
Secondary Neoplasm
0.100 AlteredExpression group BEFREE The expression of metastasis associated protein (MTA1) correlates well with tumor metastasis; however its role as a proangiogenic protein and the molecular mechanisms underlying the same are not fully understood. 24265228 2015
CUI: C2939419
Disease: Secondary Neoplasm
Secondary Neoplasm
0.100 Biomarker group BEFREE The metastasis-associated gene 1 (MTA1) has been identified as one critical regulator of tumor metastasis. 23718732 2013
CUI: C2939419
Disease: Secondary Neoplasm
Secondary Neoplasm
0.100 Biomarker group BEFREE Although metastasis associated protein 1 (MTA1) has been widely linked to tumor metastasis, the relevant mechanisms remain to be elucidated, especially in colorectal cancer (CRC). 23371285 2013
CUI: C2939419
Disease: Secondary Neoplasm
Secondary Neoplasm
0.100 Biomarker group BEFREE MTA1(metastasis associated-1) is a tumor metastasis associated candidate gene and overexpression in many human tumors, including breast cancer. 21595884 2011
CUI: C2939419
Disease: Secondary Neoplasm
Secondary Neoplasm
0.100 AlteredExpression group BEFREE Although metastasis-associated protein 1 (MTA1), a component of the nucleosome remodeling and histone deacetylation complex, is widely up-regulated in human cancers and correlates with tumor metastasis, its regulatory mechanism and related signaling pathways remain unknown. 21555589 2011
CUI: C2939419
Disease: Secondary Neoplasm
Secondary Neoplasm
0.100 Biomarker group BEFREE In this study, the authors identified a panel of such markers that have been implicated in tumorigenicity, metastasis, and hormone production and hypothesized that transcript levels of the genes melanoma antigen family D2 (MAGE-D2), metastasis-associated 1 (MTA1), nucleosome assembly protein 1-like (NAP1L1), Ki-67 (a marker of proliferation), survivin, frizzled homolog 7 (FZD7), the Kiss1 metastasis suppressor (Kiss1), neuropilin 2 (NRP2), and chromogranin A (CgA) could be used to define primary SI NETs and to predict the development of metastases. 19197975 2009
CUI: C2939419
Disease: Secondary Neoplasm
Secondary Neoplasm
0.100 AlteredExpression group BEFREE The expression of metastasis-associated protein 1 (MTA1) correlates well with tumor metastases; however, the associated molecular mechanism is not fully understood. 16511565 2006
CUI: C2939419
Disease: Secondary Neoplasm
Secondary Neoplasm
0.100 AlteredExpression group BEFREE MAGE-D2 and MTA1 were increased (P < .05) in primary tumors and metastases and overexpressed in carcinomas. 16424981 2006
CUI: C2939419
Disease: Secondary Neoplasm
Secondary Neoplasm
0.100 Biomarker group BEFREE Tumor metastasis-associated human MTA1 gene and its MTA1 protein product: role in epithelial cancer cell invasion, proliferation and nuclear regulation. 12650603 2003
CUI: C2939419
Disease: Secondary Neoplasm
Secondary Neoplasm
0.100 GeneticVariation group BEFREE Tumor metastasis-associated human MTA1 gene: its deduced protein sequence, localization, and association with breast cancer cell proliferation using antisense phosphorothioate oligonucleotides. 10967548 2000