SLC16A4, solute carrier family 16 member 4, 9122

N. diseases: 114; N. variants: 1
Disease: Renal Cell Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma 		0.020 AlteredExpression disease BEFREE Orthotopic tumors were created in mice using human renal cell carcinoma (RCC) lines (A498, 786-O, UOK262) with varying expression of lactate dehydrogenase A (<i>LDHA</i>) which catalyzes the pyruvate-to-lactate conversion, and varying expression of monocarboxylate transporter 4 (<i>MCT4</i>) which mediates lactate export out of the cells. 30189677 2018
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma 		0.020 Biomarker disease BEFREE Genome-wide RNA interference analysis of renal carcinoma survival regulators identifies MCT4 as a Warburg effect metabolic target. 22362593 2012