EXO1, exonuclease 1, 9156

N. diseases: 87; N. variants: 22
Disease: Colorectal Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.360 GeneticVariation disease BEFREE In addition, polymorphisms of EXO1, LIG3, and PolB may modulate the risk of colorectal cancer by decreasing (PolB) or increasing (LIG3 and EXO1) the chance of malignant transformation. 26649135 2016
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.360 GeneticVariation disease BEFREE The aim of the present study was to examine the association between the L757P polymorphism at exon 13 of the EXO1 gene and the risk of CRC in Iranian patients. 20854105 2010
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.360 Biomarker disease CTD_human MLH3 and EXO1 alterations in familial colorectal cancer patients not fulfilling Amsterdam criteria. 17656264 2007
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.360 GeneticVariation disease BEFREE The EXO1 genotypes were not associated with any clinicopathological characteristics in colorectal cancer patients. 15550454 2005
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.360 GeneticVariation disease BEFREE Hereditary non-polyposis colorectal cancer and the role of hPMS2 and hEXO1 mutations. 14756672 2004
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.360 GeneticVariation disease BEFREE In one recent study, germline variants of EXO1 were reported to be associated with predisposition to colorectal cancer in families with phenotypes similar to hereditary nonpolyposis colon cancer (HNPCC). 14623461 2003
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.360 GeneticVariation disease BEFREE We evaluated a series of European CRC patients and population controls to clarify whether EXO1 variants may indeed predispose to familial CRC. 12517792 2003