EXO1, exonuclease 1, 9156

N. diseases: 87; N. variants: 22
Disease: Breast Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.430 AlteredExpression disease BEFREE High expression level of EXO1 protein was significantly associated with poor OS in breast cancer patients (p=0.03). 31777591 2019
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.430 GeneticVariation disease GWASCAT Association analysis identifies 65 new breast cancer risk loci. 29059683 2017
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.430 Biomarker disease BEFREE We tested seven polymorphisms in DNA repair genes XRCC1, ERCC2, XRCC3, XRCC2, EXOI and TP53 for a possible association with breast cancer risk in a sample of 672 case and 672 control Russian women. 25537147 2016
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.430 Biomarker disease CTD_human Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer. 25751625 2015
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.430 GeneticVariation disease GWASCAT Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer. 25751625 2015
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.430 GeneticVariation disease BEFREE Our results provide evidence that the A allele of EXO1 K589E may be associated with the development of breast cancer and may be a useful biomarker for breast cancer detection and primary prevention. 19846925 2009