|
Body Height
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
|
Triglycerides measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genetic analyses of diverse populations improves discovery for complex traits.
|
31217584 |
2019 |
|
Triglycerides measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
A large electronic-health-record-based genome-wide study of serum lipids.
|
29507422 |
2018 |
|
High density lipoprotein measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
A large electronic-health-record-based genome-wide study of serum lipids.
|
29507422 |
2018 |
|
Serum total cholesterol measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
A large electronic-health-record-based genome-wide study of serum lipids.
|
29507422 |
2018 |
|
Blood Protein Measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genomic atlas of the human plasma proteome.
|
29875488 |
2018 |
|
Triglycerides measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genome-wide association study of serum lipids confirms previously reported associations as well as new associations of common SNPs within PCSK7 gene with triglyceride.
|
26763881 |
2016 |
|
Triglycerides measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks.
|
24507774 |
2014 |
|
High density lipoprotein measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks.
|
24507774 |
2014 |
|
Pyloric Stenosis, Hypertrophic
|
0.100 |
GeneticVariation
|
disease |
GWASDB |
Plasma lipids, genetic variants near APOA1, and the risk of infantile hypertrophic pyloric stenosis.
|
23989729 |
2013 |
|
Low density lipoprotein cholesterol measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASDB |
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
|
23063622 |
2012 |
|
Triglycerides measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASDB |
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
|
23063622 |
2012 |
|
Serum LDL cholesterol measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASDB |
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
|
23063622 |
2012 |
|
Pyloric Stenosis, Hypertrophic
|
0.100 |
GeneticVariation
|
disease |
GWASDB |
Common variants near MBNL1 and NKX2-5 are associated with infantile hypertrophic pyloric stenosis.
|
22306654 |
2012 |
|
Triglycerides measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits.
|
21943158 |
2011 |
|
Pseudocholinesterase Measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASDB |
Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits.
|
21943158 |
2011 |
|
Soluble Transferrin Receptor Measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Novel association to the proprotein convertase PCSK7 gene locus revealed by analysing soluble transferrin receptor (sTfR) levels.
|
21149283 |
2011 |
|
Neoplasms
|
0.040 |
AlteredExpression
|
group |
BEFREE |
Also, in vivo tumor therapy experiments demonstrated that the longest survival period along with the greatest downregulation of EGFR expression in tumor tissues was observed in mice with an intracranial U87 glioma treated with T7-LPC/siEGFR NPs compared with mice receiving other formulations.
|
27374198 |
2016 |
|
Neoplasms
|
0.040 |
Biomarker
|
group |
BEFREE |
Furthermore, the experiments of in vivo tumor therapy confirmed that intravenous administration of T7-LPC/siEGFR NPs led to an effective EGFR down-regulation and an obvious inhibition of breast tumor growth, with little activation of immune responses and negligible body weight loss.
|
27355138 |
2016 |
|
Neoplasms
|
0.040 |
Biomarker
|
group |
BEFREE |
Thus, it was concluded that LPC-T is an effective carrier for passive targeting of the pulmonary tissue, treatment of Renca-induced pulmonary metastases, and local administration of Renca cell SC tumors.
|
15194050 |
2004 |
|
Neoplasms
|
0.040 |
Biomarker
|
group |
BEFREE |
As a first step towards elucidating the role that pro-protein convertases play in the growth regulation of breast cancer, we studied the gene expression of 6 known human convertase members (PC1/PC3, PC2, furin/PACE, PACE4, PC5/PC6 and PC7/LPC) in human breast cancer tumors and cell lines.
|
9185698 |
1997 |
|
Liver Cirrhosis
|
0.030 |
Biomarker
|
disease |
BEFREE |
MERTK and PCSK7 SNPs were not associated with liver fibrosis or cirrhosis.
|
28338112 |
2017 |
|
Fibrosis, Liver
|
0.030 |
Biomarker
|
disease |
BEFREE |
MERTK and PCSK7 SNPs were not associated with liver fibrosis or cirrhosis.
|
28338112 |
2017 |
|
Cirrhosis
|
0.030 |
Biomarker
|
disease |
BEFREE |
MERTK and PCSK7 SNPs were not associated with liver fibrosis or cirrhosis.
|
28338112 |
2017 |
|
Liver Cirrhosis
|
0.030 |
GeneticVariation
|
disease |
BEFREE |
We evaluated PCSK7 alleles and genotypes frequencies according to single or grouped staging scores: absent/mild fibrosis (stage: 0-2), moderate (stage: 3-4), and severe fibrosis/cirrhosis (stage: 5-6).
|
26868056 |
2016 |