NEXN, nexilin F-actin binding protein, 91624

N. diseases: 36; N. variants: 8
Disease: Cardiomyopathy, Dilated ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007193
Disease: Cardiomyopathy, Dilated
Cardiomyopathy, Dilated 		0.110 GeneticVariation group CLINVAR Nexilin mutations destabilize cardiac Z-disks and lead to dilated cardiomyopathy. 19881492 2009
CUI: C0007193
Disease: Cardiomyopathy, Dilated
Cardiomyopathy, Dilated 		0.110 GeneticVariation group BEFREE To evaluate the role of nexilin in human heart failure, we performed a genetic association study on individuals with dilated cardiomyopathy and found several mutations in NEXN associated with the disease. 19881492 2009
CUI: C0007193
Disease: Cardiomyopathy, Dilated
Cardiomyopathy, Dilated 		0.110 Biomarker group HPO