NEXN, nexilin F-actin binding protein, 91624

N. diseases: 36; N. variants: 8
Disease: Cardiomyopathies ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0878544
Disease: Cardiomyopathies
Cardiomyopathies 		0.430 Biomarker group BEFREE These results demonstrated that NEXN is a pivotal component of the junctional membrane complex and is required for initiation and formation of T-tubules, thus providing insight into mechanisms underlying cardiomyopathy in patients with mutations in NEXN. 30982350 2019
CUI: C0878544
Disease: Cardiomyopathies
Cardiomyopathies 		0.430 Biomarker group BEFREE NEXN is an F-actin binding protein and previously identified as a disease gene causing cardiomyopathies. 24866383 2014
CUI: C0878544
Disease: Cardiomyopathies
Cardiomyopathies 		0.430 Biomarker group BEFREE Xin is a striated muscle-specific F-actin binding protein that has been implicated in cardiomyopathies. 19843512 2010
CUI: C0878544
Disease: Cardiomyopathies
Cardiomyopathies 		0.430 Biomarker group GENOMICS_ENGLAND
CUI: C0878544
Disease: Cardiomyopathies
Cardiomyopathies 		0.430 Biomarker group HPO