MYOM2, myomesin 2, 9172
N. diseases: 103; N. variants: 2
Source: ALL
| Disease | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year |
|---|---|---|---|---|---|---|---|
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0.060 | Biomarker | disease | BEFREE | Recently, a recombinant RSV strain lacking the gene that encodes the matrix (M) protein (RSV M-null) was developed. | 31004010 | 2019 |
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0.060 | AlteredExpression | disease | BEFREE | We evaluated the efficacy of KPT-335 as an anti-RSV drug and show that KPT-335 inhibits XPO1-mediated nuclear export, leading to nuclear accumulation of RSV M protein and reduction in RSV levels. | 30541831 | 2019 |
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0.060 | Biomarker | disease | BEFREE | Intranasal (IN) vaccination with a murine cytomegalovirus (MCMV) vector expressing the M protein of RSV (MCMV-M) has been shown to elicit robust populations of CD8<sup>+</sup> T<sub>RM</sub> cells that accumulate over time and mediate early viral clearance. | 30154789 | 2018 |
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0.060 | Biomarker | disease | BEFREE | Purified wildtype RSV M protein was found to bind directly to polymerized actin in vitro. | 30274351 | 2018 |
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0.060 | Biomarker | disease | BEFREE | To determine how the route of immunization affects CD8+ T-cell responses in the lungs of mice vaccinated with a murine cytomegalovirus vector expressing the respiratory syncytial virus matrix (M) protein, we infected CB6F1 mice via the intranasal or intraperitoneal route and evaluated the M-specific CD8+ T-cell response at early and late time points. | 27220815 | 2017 |
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0.060 | Biomarker | disease | BEFREE | We studied the kinetics of localisation of matrix (M) protein of Human respiratory syncytial virus (RSV) in infected cells. | 12827470 | 2003 |