DCLK1, doublecortin like kinase 1, 9201

N. diseases: 123; N. variants: 17
Disease: Malignant tumor of colon ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.060 Biomarker disease BEFREE Co-localization of autophagy-related protein p62 with cancer stem cell marker dclk1 may hamper dclk1's elimination during colon cancer development and progression. 31040926 2019
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.060 AlteredExpression disease BEFREE DCLK1 expression correlates with malignant grade of colon cancer and offers a potential treatment target. 31562741 2019
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.060 Biomarker disease BEFREE A novel antibody against cancer stem cell biomarker, DCLK1-S, is potentially useful for assessing colon cancer risk after screening colonoscopy. 28414327 2017
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.060 Biomarker disease BEFREE miR-137 Regulates the Tumorigenicity of Colon Cancer Stem Cells through the Inhibition of DCLK1. 26747706 2016
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.060 AlteredExpression disease BEFREE Epigenetic changes and alternate promoter usage by human colon cancers for expressing DCLK1-isoforms: Clinical Implications. 26447334 2015
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.060 Biomarker disease BEFREE One notable example of specific up-regulation in KRAS codon 12 mutant SW48 cells is provided by the short form of the colon cancer stem cell marker doublecortin-like Kinase 1 (DCLK1) that can be reversed by suppression of KRAS. 25599653 2015