DCLK1, doublecortin like kinase 1, 9201

N. diseases: 123; N. variants: 17
Disease: Colorectal Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.310 AlteredExpression group BEFREE Human colorectal tumors (CRCs) and hCCCs express a novel short isoform of DCLK1 (DCLK1-S; isoform 2) from β-promoter of hDCLK1 gene, while normal colons express long isoform (DCLK1-L; isoform 1) from 5'(α)-promoter, suggesting that DCLK1-S, and not DCLK1-L, marks cancer stem cells (CSCs). 28414327 2017
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.310 Therapeutic group CTD_human Dclk1 distinguishes between tumor and normal stem cells in the intestine. 23202126 2013