MTSS2, MTSS I-BAR domain containing 2, 92154

N. diseases: 8; N. variants: 1
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0026827
Disease: Muscle hypotonia
Muscle hypotonia 		0.100 GeneticVariation phenotype CLINVAR
CUI: C0557874
Disease: Global developmental delay
Global developmental delay 		0.100 GeneticVariation disease CLINVAR
CUI: C1843367
Disease: Poor school performance
Poor school performance 		0.100 GeneticVariation phenotype CLINVAR
CUI: C4551563
Disease: Microcephaly (physical finding)
Microcephaly (physical finding) 		0.100 GeneticVariation phenotype CLINVAR
CUI: C0021400
Disease: Influenza
Influenza 		0.020 Biomarker disease BEFREE Therefore, the present work aims to seek influenza H7N9 virus inhibitors from natural source by synthesis of dryocrassin ABBA and its analogues. 31324565 2019
CUI: C0021400
Disease: Influenza
Influenza 		0.020 Biomarker disease BEFREE In conclusion, phloroglucinols from <i>D. crassirhizoma</i> were shown to have anti-influenza virus activity, and especially dryocrassin ABBA, one of the phloroglucinols, may have the potential to control influenza virus (H5N1) infection. 28282885 2017
CUI: C0032285
Disease: Pneumonia
Pneumonia 		0.010 Biomarker disease BEFREE An Inhibitory Effect of Dryocrassin ABBA on <i>Staphylococcus aureus</i> vWbp That Protects Mice From Pneumonia. 30728809 2019
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis 		0.010 Biomarker disease BEFREE Our ABBA analysis allowed us to propose a new role for <i>Ifitm3</i> in the pathogenesis of glomerulonephritis via a mechanism involving promoter hypermethylation that is associated with <i>Ifitm3</i> repression in the rat strain susceptible to glomerulonephritis. 28213474 2017
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.010 Biomarker disease BEFREE In this study, the apoptotic effect of dryocrassin ABBA on human hepatocellular carcinoma HepG2 cells was investigated. 27221859 2016