Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
0.060 Biomarker disease BEFREE Together our findings indicate that PBF and PTTG have a critical role in promoting thyroid cancer that is predictive of poorer patient outcome. 28504713 2017
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
0.060 Biomarker disease BEFREE This study demonstrates for the first time that drugs, such as CDODA-Me and CF(3)DODA-Me, that decrease Sp protein expression also downregulate PTTG-1 in thyroid cancer cells and therefore have potential for clinical treatment of thyroid cancer and other endocrine neoplasias where PTTG-1 is a major pro-oncogenic factor. 21268135 2011
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
0.060 AlteredExpression disease LHGDN PTTG and PBF repress the human sodium iodide symporter. 17297475 2007
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
0.060 Biomarker disease LHGDN Pituitary tumor transforming gene (PTTG) stimulates thyroid cell proliferation via a vascular endothelial growth factor/kinase insert domain receptor/inhibitor of DNA binding-3 autocrine pathway. 16926250 2006
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
0.060 Biomarker disease LHGDN Pituitary tumour transforming gene (PTTG) induces genetic instability in thyroid cells. 15897900 2005
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
0.060 AlteredExpression disease LHGDN Pituitary tumor transforming gene and fibroblast growth factor-2 expression: potential prognostic indicators in differentiated thyroid cancer. 12727994 2003