PDLIM7, PDZ and LIM domain 7, 9260

N. diseases: 241; N. variants: 1
Disease: Multiple Sclerosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.060 Biomarker disease BEFREE Infected B cell proliferation is driven by signalling through the EBV produced cell surface protein LMP1, a homologue of the MS risk gene CD40. 31039804 2019
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.060 Biomarker disease BEFREE Previously, we showed that monoclonal myelin basic protein (MBP)-specific antibodies from MS patients cross-react with Epstein-Barr virus (EBV) latent membrane protein 1 (LMP1). 28729867 2017
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.060 Biomarker disease BEFREE Structural alignment of 13 clones selected toward myelin basic protein (MBP), one of the major myelin antigens, showed high homology within variable regions with cerebrospinal fluid MS-associated antibodies as well as with antibodies toward Epstein-Barr latent membrane protein 1 (LMP1). 21859892 2011
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.060 Biomarker disease BEFREE The goal of this study was to attempt to demonstrate LMP1 by IHC and EBER by ISH in brains of patients with MS, to either support or refute their findings. 21494180 2011
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.060 GeneticVariation disease BEFREE No individual variants in LMP1 were associated with risk of MS (all P > 0.05). 20636447 2011
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.060 Biomarker disease BEFREE We found a variety of LMP-1 sequences in both MS and controls, with no significant differences between the groups. 18184350 2008