Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1707291
Disease: NUT midline carcinoma
NUT midline carcinoma
0.020 Biomarker disease BEFREE Recently, BET inhibitors and histone deacetylase inhibitors have emerged as two promising classes of targeted agents, currently investigated in clinical trials for adults with head and neck NMC. 31118674 2019
CUI: C1707291
Disease: NUT midline carcinoma
NUT midline carcinoma
0.020 AlteredExpression disease BEFREE The most successful approaches that have been clinically validated so far include the targeting of the BRD4-NUT fusion transcript in NUT-midline carcinoma by BET (Bromodomain Extra-Terminal) inhibitors, and the use of EZH2 (Enhancer of Zest Homolog 2) inhibitors in SMARCB1-deficient malignant rhabdoid tumors and SMARCA4-deficient ovarian small cell carcinomas. 28426098 2017