|
Neoplasms
|
0.040 |
GeneticVariation
|
group |
BEFREE |
Moreover, a detailed analysis of a frequently deleted region at 3p21.3 (CER1) showed associations between tumor breaks and gene duplications.
|
18230801 |
2008 |
|
Neoplasms
|
0.040 |
Biomarker
|
group |
BEFREE |
CER1 - our main focus - contains multiple genes that may inhibit tumor growth, but 3 genes, RIS1, LF (LTF) and LIMD1 have already the necessary experimental support to be considered bona fide tumor suppressors.
|
17174104 |
2007 |
|
Neoplasms
|
0.040 |
Biomarker
|
group |
BEFREE |
It belongs to a novel family of bone morphogenetic protein (BMP) antagonists that includes the head-inducing factor Cerberus and the tumour suppressor DAN.
|
12386293 |
2002 |
|
Neoplasms
|
0.040 |
Biomarker
|
group |
BEFREE |
We now report that CER1 contains 14 markers that are deleted in 19 SCID-derived tumors.
|
10610706 |
1999 |
|
Autism Spectrum Disorders
|
0.010 |
Biomarker
|
disease |
BEFREE |
Cerberus is implemented and evaluated in the context of the GENIDA project, an international CSP for Genetically determined Intellectual Disabilities and Autism Spectrum Disorders.
|
29159559 |
2017 |
|
Intellectual Disability
|
0.010 |
Biomarker
|
group |
BEFREE |
Cerberus is implemented and evaluated in the context of the GENIDA project, an international CSP for Genetically determined Intellectual Disabilities and Autism Spectrum Disorders.
|
29159559 |
2017 |
|
Premature Menopause
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
CER1 gene variations associated with bone mineral density, bone markers, and early menopause in postmenopausal women.
|
24138842 |
2013 |
|
Osteoporosis
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
No significant association between the studied DKK1 variations and osteoporosis was found, while CER1 variations seem to play a significant role in the determination of osteoporosis and a potential predictive role, combined with bone markers, in postmenopausal osteoporotic women.
|
24138842 |
2013 |
|
Osteoporotic Fractures
|
0.010 |
GeneticVariation
|
group |
BEFREE |
Novel sequence variations in the CER1 gene are strongly associated with low bone mineral density and risk of osteoporotic fracture in postmenopausal women.
|
22543871 |
2012 |
|
Trigonocephaly
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
FGFR1 (exon 7), CER1, and CDON are not related to trigonocephaly in our sample and should not be considered as causative genes for metopic synostosis.
|
16526918 |
2006 |
|
Metopic synostosis
|
0.010 |
Biomarker
|
disease |
BEFREE |
FGFR1 (exon 7), CER1, and CDON are not related to trigonocephaly in our sample and should not be considered as causative genes for metopic synostosis.
|
16526918 |
2006 |
|
Fibrosarcoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
By passaging microcell hybrids (MCHs) containing human chromosome 3 (chr3) on A9 mouse fibrosarcoma background through severe combined immunodeficient (SCID) mice (elimination test), we have previously defined a 1-Mb-long common eliminated region 1 (CER1) at 3p21.3, a second eliminated region (ER2) at 3p21.1-p14 and a common retained region (CRR) at 3q26-qter.
|
11158607 |
2001 |
|
Adult Fibrosarcoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
By passaging microcell hybrids (MCHs) containing human chromosome 3 (chr3) on A9 mouse fibrosarcoma background through severe combined immunodeficient (SCID) mice (elimination test), we have previously defined a 1-Mb-long common eliminated region 1 (CER1) at 3p21.3, a second eliminated region (ER2) at 3p21.1-p14 and a common retained region (CRR) at 3q26-qter.
|
11158607 |
2001 |
|
Severe Combined Immunodeficiency
|
0.010 |
Biomarker
|
disease |
BEFREE |
A 1-Mb PAC contig spanning the common eliminated region 1 (CER1) in microcell hybrid-derived SCID tumors.
|
10610706 |
1999 |