SLIT2, slit guidance ligand 2, 9353

N. diseases: 177; N. variants: 3
Disease: Fibrosis, Liver ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0239946
Disease: Fibrosis, Liver
Fibrosis, Liver 		0.030 Biomarker disease BEFREE In conclusion, Slit2 is involved in the activation of HSCs and liver fibrogenesis, highlighting Slit2 as a potential therapeutic target for liver fibrosis. 31545977 2019
CUI: C0239946
Disease: Fibrosis, Liver
Fibrosis, Liver 		0.030 Biomarker disease BEFREE The present study provides evidence that Slit2/Robo2 signaling mediates the pathogenesis of hepatic fibrogenesis and regulates HSCs biology, thus providing potential markers for HSCs, and therapeutic and diagnostic target toward liver fibrosis. 29660433 2018
CUI: C0239946
Disease: Fibrosis, Liver
Fibrosis, Liver 		0.030 Biomarker disease BEFREE Development of hepatic fibrosis in Slit2-Tg mice was associated with a stronger hepatic expression of collagen I and α-smooth muscle actin (α-SMA). 26264936 2015