SLIT2, slit guidance ligand 2, 9353

N. diseases: 177; N. variants: 3
Disease: Osteosarcoma of bone ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone 		0.020 Biomarker disease BEFREE Taken together, the findings reveal a previously unappreciated function of SLIT2/ROBO1 signaling in OS, which is intertwined with metabolic alterations that promote cancer progression. 29523788 2018
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone 		0.020 Biomarker disease BEFREE Sarcoma inoculation induces excitatory synaptogenesis and bone cancer pain which are reversed by Slit2 knockdown but aggravated by Robo1 knockdown. 26738857 2017