SLC22A6, solute carrier family 22 member 6, 9356

N. diseases: 19; N. variants: 1
Disease: Kidney Failure, Acute ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute 		0.030 Biomarker disease BEFREE This study examined and identified the effect of AMI-induced AKI on organic anion transporter 1 (Oat1) and Oat3 transport using clinical setting of pre-renal AKI in vivo. 31125610 2019
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute 		0.030 AlteredExpression disease BEFREE The molecular mechanism of decreased expression of Oat1 and Oat3 was achieved through activating p53, and then increasing the expression of Bax and Caspase-3 and down regulating Bcl-2 in AKI rats. 30047127 2018
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute 		0.030 AlteredExpression disease BEFREE Recently, we gained evidence that impairment of rOat1 and rOat3 expression induced by ischemic acute kidney injury (AKI) is mediated by COX metabolites and this suppression might be critically involved in renal damage. 26277839 2015