MYOCD, myocardin, 93649

N. diseases: 79; N. variants: 7
Disease: Aortic Stiffness ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C3178782
Disease: Aortic Stiffness
Aortic Stiffness 		0.020 Biomarker phenotype BEFREE We here hypothesized that Rho kinase (ROCK) acts as a novel mediator that regulates intrinsic VSMC mechanical properties through the serum response factor (SRF) /myocardin pathway and consequently regulates aortic stiffness and blood pressure in hypertension. 29169155 2017
CUI: C3178782
Disease: Aortic Stiffness
Aortic Stiffness 		0.020 Biomarker phenotype BEFREE Inhibition of SRF/myocardin reduces aortic stiffness by targeting vascular smooth muscle cell stiffening in hypertension. 28003268 2017