KL, klotho, 9365

N. diseases: 332; N. variants: 20
Disease: Obesity ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0028754
Disease: Obesity
Obesity 		0.030 Biomarker disease BEFREE Urinary excretion of Klotho was higher in ZO rats at 2, 5, and 8 months of study, plasma Klotho levels were reduced and protein abundance of Klotho in renal tissue was similar in ZL and ZO rats. 30483154 2018
CUI: C0028754
Disease: Obesity
Obesity 		0.030 AlteredExpression disease BEFREE There was similarly no association between klotho levels at birth and future obesity at age 2. 29648999 2018
CUI: C0028754
Disease: Obesity
Obesity 		0.030 Biomarker disease BEFREE However, further studies are needed to explore the possibility that Klotho could be a novel therapeutic target to reduce obesity and related complications, and to determine whether and how Klotho might influence the regulation and function of a related protein, β-Klotho, which is also involved in energy metabolism. 22641000 2012