KL, klotho, 9365

N. diseases: 332; N. variants: 20
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0233794
Disease: Memory impairment
Memory impairment
0.310 AlteredExpression phenotype BEFREE Lentivirus-mediated klotho up-regulation improves aging-related memory deficits and oxidative stress in senescence-accelerated mouse prone-8 mice. 29544758 2018
CUI: C0233794
Disease: Memory impairment
Memory impairment
0.310 Biomarker phenotype CTD_human Melatonin attenuates oxidative stress and the associated memory impairment induced by klotho deficiency via signaling interaction between the MT2 receptor and ERK- and Nrf2-related antioxidant potential. 25550330 2014
CUI: C0233794
Disease: Memory impairment
Memory impairment
0.310 Biomarker phenotype CTD_human Growth Hormone-Releaser Diet Attenuates Cognitive Dysfunction in Klotho Mutant Mice via Insulin-Like Growth Factor-1 Receptor Activation in a Genetic Aging Model. 25309793 2014